Malariology
Spring 2006
Instructors
Clive Shiff, Nirbhay Kumar, and David Sullivan
Offered By
Molecular Microbiology and Immunology
Description
Presents issues related to malaria as a major public health problem. Emphasizes the biology of malaria parasites and factors affecting their transmission to humans by anopheline vectors. Topics include host-parasite-vector relationships; diagnostics; parasite biology; vector biology; epidemiology; host immunity; risk factors associated with infection, human behavior, chemotherapy, and drug resistances; anti-vector measures; vaccine development; and management and policy issues.
OCW offers a snapshot of the educational content offered by JHSPH. OCW materials are not for credit towards any degrees or certificates offered by the Johns Hopkins Bloomberg School of Public Health.
Syllabus
Course Description
Presents issues related to malaria as a major public health problem. Emphasizes the biology of malaria parasites and factors affecting their transmission to humans by anopheline vectors. Topics include host-parasite-vector relationships; diagnostics; parasite biology; vector biology; epidemiology; host immunity; risk factors associated with infection, human behavior, chemotherapy, and drug resistances; anti-vector measures; vaccine development; and management and policy issues.
Course Objectives
1. Understand the complex relationships between host and vector that affect transmission and control.
2. Integrate the host and parasite relationships to understand the immune response, nature of disease and disease manifestations.
3. Interpret epidemiological indices associated with patterns of malaria transmission.
4. Evaluate different approaches to malaria control, either through vector control, chemotherapy and vaccines when they become available.
5. Understand the differences between the various species of Plasmodium affecting humans.
Schedule
This course is an in-depth analysis of malaria biology, epidemiology, pathology, immunology diagnosis and treatment, malaria control and mosquito vector entomolgy and insecticide control.
| 1 |
Malaria Overview
David Sullivan
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| 2 |
Malariology: Biology of the Parasite
Nirbhay Kumar
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| 3 |
Malaria Epidemiology
Clive Shiff
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| 4 |
Malaria Entomology
Douglas E. Norris
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| 5 |
Insecticide Resistance and Mosquito Population Biology
Douglas E. Norris
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| 6 |
Genomic Analyses of Anopheles-Plasmodium Interactions
George Dimopoulos
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| 7 |
Genetic Approaches for Malaria Control
Marcelo Jacobs-Lorena
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| 8 |
Malaria Control
Clive Shiff
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| 9 |
Behavior Change Interventions for Malaria Programs
Peter Winch
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| 10 |
Immunity to Malaria
Fidel Zavala
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| 11 |
Immunopathogenesis of Malaria
Chris Ockenhouse
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| 12 |
Malaria Chemotherapy & Drug Resistance
David Sullivan
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| 13 |
Drug Resistance and Population Genetics of Malaria
Christopher Plowe
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| 14 |
Malaria: Targets for New Drugs
Sean Prigge
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| 15 |
Diagnosis and Clinical Complications
David Sullivan
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| 16 |
Malaria Vaccines: Trials and Tribulations
Lee Hall
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